Bipolar Disorder Diagnosis And Treatment

Bipolar Disorder: Analysis and Treatment

  • Introduction

    Bipolar problem (formerly manic depression) is a serious and common psychiatric problem affecting a person’s feeling. The moods swing from one extreme to another- feeling very low and weary and feeling very high and overactive. These moods dysfunctions i actually.e, melancholia and mania have been documented repeatedly in human history. First descriptions were made by Hippocrates, Falret and Baillarger, and Kraepelin in the 19 th century (Mason et al. 3). The causes of the condition are unidentified, although various incidences including extreme anxiety, overpowering problems, and life-changing activities have been related with it.


    The disorder is recognized as a neuroprogressive abnormality with a cumulative risk of relapse for each and every new episode and with increasing cognitive disabilities during the course of illness. It affects nearly 1% of the population globally and is the chief cause of hospitalizations, health care expenditures, and suicide (Oedegaard et al. 2). The onset of bipolar problem is projected to be 25 years, and roughly 34% individuals have an inception under the age of 19 years. Reports have found a “bimodal distribution of age onset, with a peak in past due teenage and a minor, but yet substantial, peak in mid-daily life” (Kessing et al. 544). It affects folks from all races and backgrounds similarly.

    Signs or symptoms

    The outward symptoms of bipolar disorder be determined by the mood being felt and could last weeks. Early prognostic warning signs include depression, which is along with a good sense of worthlessness, hopelessness, and suicidal views. The manic period of the dysfunction is portrayed by extreme thoughts of contentment, invigorated, having aspiring ideas and big ideas.

    Bipolar Sickness and Pregnancy

    The condition will probably appear or worsen during or after maternity. It really is imperative that any signal of depression and manic instance be diagnosed and treated consequently. Hazards of untreated perinatal bipolar dysfunction comprise preterm labor, underweight young children, raised levels of fetal stress and anxiety hormones, alterations in neurobehavioral work of the newborn, and influence on mother-infant binary exchanges. Careful evaluation is vital to distinguish between depression because of unipolar disorder and that because of bipolar disorder.


    The disorder is really a highly treatable and manageable state. Baldessarini and Tarazi remember that “the backbone of clinical operations of bipolar disorder is certainly stabilization and prophylaxis by usage of mood-stabilizing pharmacological agents to reduce both manic and melancholic signs” (1245). However, these therapeutic brokers tend to be more effective in the manic period of the illness. Lithium may be the mainstay of remedy with the strongest files for both efficacy and suicide avoidance, despite the fact that reports of non-response to the medication among some patients have already been documented (Mason et al. 4). Furthermore, a number of sufferers are intolerant to prolonged use of lithium due to side effects such as weight gain, acne pimples, thyroid suppression, and renal impairment (Oedegaard et al. 3). Therefore, efforts aimed at finding different antimanic and feeling stabilizing agents have elevated and borne fruits. Other mood stabilizers, developed because of this, contain some anticonvulsants e.g., valproate, carbamazepine, and lamotrigine.

    Atypical antipsychotics such as olanzapine, risperidone, aripiprizole and quetiapine are also efficacious. These drugs have been found to generate their mood-stabilizing results through their actions on different biochemical pathways. For instance, they inhibit cAMP and cGMP creation by catecholamines, inhibit inositol signalling mechanisms and other pathways involved in cell survival, and repress gene expression of various proteins involved in the pathogenesis of bipolar problem.

    Other forms of treatment include talking treatment that will help one to deal with depression, and provide advice on better socializing. In addition, lifestyle advice, i.e., regular exercise, improved diet and getting more sleep is helpful.


    Even though bipolar disorder has several debilitating effects on the life of a patient, a good treatment program can curb mood swings and provide symptom relief. A combination of medication and psychotherapy is effective. Ongoing treatment, rather than dealing with problems as they arise, is usually preferable.

    Works Cited

    Baldessarini, Ross and Frank Tarazi. Pharmacotherapy of Psychosis and Mania: Goodman & Gilman’s the Pharmacological Foundation of Therapeutics . McGraw- Hill, 2006.

    Kessing, Lars Vedel, et al. “Life Expectancy in Bipolar Problem.” Bipolar Disorders: An International Journal of Psychiatry and neurosciences, vol. 17, simply no. 1, 2015, pp. 543-548.

    Mason, Brittany, et al. “Historic Underpinnings of Bipolar Problem Diagnostic Requirements.” Behavioral Sciences, vol. 14, simply no. 6, 2016, pp. 1-19.

    Oedegaard, Ketil, et al. “The Pharmacogenomics of Bipolar Problem research (PGBD): Identification of Genes for Lithium Reaction in a Potential Sample.” BMC Psychiatry, vol. 129, simply no. 16, 2016, p

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